Ten patients with chronic liver disease, whose serum levels of AFP were markedly increased, were detected from Jan. 1985 to Sep. 1990.
The clinical and laboratory findings were examined and the results were as follows.
1. The objective patients were 4 males and 6 females, and their mean age was 40.2 years old. Five cases were chronic active hepatitis-B, and the other 5 cases were liver cirrhosis.
2. At the time of first examination, the mean level of serum AFP was 499mg/ml and this initial level of AFP declined to 10.4ng/ml after 5.1 monthes.
3. Initially the mean levels of serum AST, ALT and ALP were 271.7, 299.1 and 177.1 IU/L, and after 5.1 monthes these levels were changed to 61.0, 53.6 and 72.1 IU/L.
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